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SUMMARY OF MEETING: B cell-T cell collaboration leads, via the germinal center reaction, to the generation of B cell memory and long-lived affinity-matured protective antibodies. This key immune response has been extensively studied, and, as a result, we have an increasingly refined understanding of the ligands, receptors, and intra-cellular pathways that are involved. However, many aspects of this remarkable process as it plays out in infections, vaccine responses, and chronic immunological diseases remain unknown. In particular, we still do not…